When anticipating pain, the brains of people with depression kick into overdrive and hinder their ability to handle hurt, a new study shows. Brain imaging also reveals that during the painful experience, activity then decreases in other areas, including those regions that handle pain modulation.
“The anticipatory brain response may indicate hypervigilance to impending threat, which may lead to increased helplessness and maladaptative
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depression, Makes, More, Pain, Sensitive
When anticipating pain, the brains of subjects with major depressive disorder appear to react more strongly, and appear to display altered functioning of the neural network that moderates pain sensitivity.
Patients with depression tended to have increased activation in specific areas of the brain, including the right amygdala, when they anticipated painful stimuli, in comparison to the reactions of

the controls.
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Altered, depression, Pain, Patients, Response, Shown
The brains of those with major depressive disorder appear to react more strongly when pain is anticipated and also show altered functioning of the neural network that modifies pain sensitivity, according to a new report.
Chronic pain and depression are common and often overlap each other, say study authors Irina A. Strigo and her colleagues at the University of California San Diego, LaJolla. Recurring or chronic pain occurs in 75%
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between, depression, link, Pain, Reveal, Studies
According to a recent study, the brains of individuals with major depressive disorder appear to react more strongly when anticipating pain and also display altered functioning of the neural network that modifies pain sensitivity.
Chronic pain and depression are common and often overlapping syndromes. Recurring or chronic pain occurs in more than 75 percent of patients with depression, and between 30 percent and 60 percent of patients
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between, depression, Pain, Relationship, Reveals